What happens when two comfort-food favorites come together? You get Pizza Enchiladas—soft tortillas packed with savory pizza toppings, plenty of melted cheese, and a rich tomato sauce, then baked until bubbly and golden.
This easy casserole is perfect for busy weeknights, family dinners, or whenever you’re craving pizza but want something a little different. It’s customizable, freezer-friendly, and guaranteed to disappear quickly from the dinner table.
Ingredients
For the Enchiladas
- 8 medium flour tortillas
- 2 cups shredded mozzarella cheese
- 1 cup shredded cheddar cheese
- 1 cup sliced pepperoni, chopped
- ½ cup cooked Italian sausage, crumbled
- ½ cup sliced mushrooms
- ½ cup diced bell pepper
- ¼ cup sliced black olives
- ¼ cup finely diced onion
- 2 tablespoons grated Parmesan cheese
For the Pizza Sauce
- 2 cups pizza sauce or marinara sauce
- 1 teaspoon Italian seasoning
- ½ teaspoon garlic powder
- ½ teaspoon onion powder
- ¼ teaspoon red pepper flakes, optional
- 1 tablespoon tomato paste, optional
For Topping
- 1 cup shredded mozzarella cheese
- ¼ cup sliced pepperoni
- 2 tablespoons grated Parmesan
- 1 teaspoon Italian seasoning
- Fresh basil or parsley, optional
Instructions
1. Prepare the Sauce
Preheat your oven to 375°F (190°C).
In a bowl, combine the pizza sauce, Italian seasoning, garlic powder, onion powder, and red pepper flakes if using.
Stir well and set aside.
2. Prepare the Filling
In a large bowl, combine:
- 1 cup mozzarella
- ½ cup cheddar
- Chopped pepperoni
- Cooked Italian sausage
- Mushrooms
- Bell pepper
- Onion
- Black olives
- Parmesan
Mix until everything is evenly distributed.
3. Assemble the Enchiladas
Spread about ½ cup of the pizza sauce across the bottom of a 9 × 13-inch baking dish.
Warm the tortillas for a few seconds in the microwave so they’re easier to roll.
Place approximately ½ cup of the pizza filling down the center of each tortilla.
Roll each tortilla tightly and place it seam-side down in the baking dish.
Repeat with the remaining tortillas.
4. Add the Sauce and Cheese
Pour the remaining pizza sauce over the tops of the rolled tortillas, spreading it evenly.
Sprinkle the remaining mozzarella and cheddar over the top.
Add the sliced pepperoni and Parmesan.
Finish with a little Italian seasoning.
5. Bake
Cover the baking dish loosely with aluminum foil.
Bake for 20 minutes.
Remove the foil and continue baking for another 10–15 minutes, until the cheese is melted, bubbling, and lightly golden around the edges.
For an extra golden top, place it under the broiler for 1–2 minutes, watching carefully so it doesn’t burn.
6. Rest and Serve
Allow the Pizza Enchiladas to rest for about 5 minutes before serving.
Garnish with fresh basil or parsley if desired.
Slice and serve warm.
Helpful Tips
Don’t overfill the tortillas: Too much filling can make them difficult to roll and may cause them to split.
Warm the tortillas first: A few seconds in the microwave makes flour tortillas much more flexible.
Use freshly shredded cheese: It generally melts more smoothly than pre-shredded cheese.
Keep the sauce generous: The sauce helps prevent the tortillas from drying out during baking.
Watch the salt: Pepperoni, sausage, Parmesan, and cheese can already provide plenty of salt, so additional salt may not be necessary.
Easy Variations
Supreme Pizza Enchiladas
Add cooked ground beef, extra bell peppers, mushrooms, onions, and black olives.
Chicken Pizza Enchiladas
Replace the sausage with shredded cooked chicken and add diced roasted peppers.
Vegetarian Pizza Enchiladas
Skip the meat and add mushrooms, bell peppers, spinach, onions, olives, and extra cheese.
Spicy Pizza Enchiladas
Add sliced jalapeños, crushed red pepper flakes, or spicy Italian sausage.
Hawaiian-Style
Add diced cooked ham and small pieces of pineapple for a sweet-and-savory combination.
What to Serve With Pizza Enchiladas
These enchiladas are filling on their own, but you can serve them with:
- A crisp green salad
- Garlic bread
- Roasted vegetables
- Steamed broccoli
- Caesar salad
- A simple cucumber and tomato salad
Storage
Store leftovers in an airtight container in the refrigerator for up to 3–4 days.
To reheat, place individual portions in the microwave until hot, or cover and warm them in a 350°F (175°C) oven until heated through.
You can also assemble the casserole ahead of time, cover it tightly, refrigerate, and bake when ready. If baking directly from the refrigerator, allow a little additional cooking time.
Final Thoughts
Pizza Enchiladas are the perfect mash-up for anyone who can’t decide between pizza night and Mexican-inspired comfort food. With saucy tortillas, gooey cheese, pepperoni, sausage, and your favorite pizza toppings, every bite is packed with familiar flavors in a completely new form.
They’re easy enough for a weeknight but fun enough to make when you’re feeding a crowd. Customize the filling with whatever pizza toppings your family loves and make this cheesy casserole your own.